Human Sera
Cayman Chemical Buparvaquon 100mg
An inhibitor of cytochrome bc1 in the parasites T. annulata and T. parva (in vitro EC50 of 1.5 x 10-8 M and 6.1 x 10-10 M, respectively)
Cayman Chemical TerpInolen 100mg
A monoterpene; found in the essential oils of various plants, including C. sativa; has diverse biological activities; inhibits expression of AKT1 in Jurkat and K562 cells by 95% at 0.05%; inhibits the growth of K562 cells at 0.01%; inhibits the growth of HT-29, Hep-2, NCI-292, and HL-60 cells (IC50s = 16.7, 13.7, 17.4, and 28.8 μg/ml, respectively); increases TAC in cultured human blood cells at 10-75 mg/L, but decreases cell viability at ≥150 mg/L
Cayman Chemical D-LysIn lactam 50mg
A chiral building block; has been used in the synthesis of a chiral synthetic antibiotic intermediate, as well as in the stereoselective synthesis of NK receptor antagonists
Cayman Chemical CnabIdIvarIn 50mg
An analytical reference standard categorized as a phytocannabinoid; considered an impurity in the commercial preparations of cannabidiol; intended for research and forensic applications
Cayman Chemical GemIglIptIntartrate 100mg
A DPP-4 inhibitor (IC50 = 0.01 µM); selective for DPP-4 over DPP-8, DPP-9, and FAP- α (IC50s = 277.28, 233.72, 418.43 µM, respectively); inhibits DPP-4 activity in isolated human plasma (IC50 = 11.5 nM); scavenges methylglyoxal in vitro and inhibits AGE formation between BSA and methylglyoxal and cross-linking of AGE-BSA with rat tail tendon collagen (IC50s = 1.15, 11.69, and 1.39 mM, respectively); reduces the levels of circulating AGE and red blood cell IgG content in db/db diabetic mice at 100 mg/kg; decreases blood glucose and HbA1c levels and reduces pancreatic β-cell damage in a mouse model of STZ- and high-fat diet-induced diabetes; induces cytotoxicity in SW1736 and TPC-1 cells
Cayman Chemical D-OrnIthIn lactam 50mg
A building block; has been used in the synthesis of HCV NS5B inhibitors, as well as αVβ3 integrin receptor antagonists
Cayman Chemical BarnIdIpInhydrochlorIde 100mg
A calcium channel blocker that selectively antagonizes cardiovascular calcium channels; demonstrates antihypertensive activity by reducing peripheral vascular resistance; decreases blood pressure in spontaneously hypertensive rats
Cayman Chemical Momordca grosvenor Mogrl 50mg
An aglycone with diverse biological activities; inhibits the proliferation and migration of A549, H1299, H1975, and SK-MES-1 lung cancer cells from 10-50 µM; induces AMPK activation and autophagy, as well as apoptosis and cell cycle arrest at the G1 phase in A549 cells at 50 µM; reduces tumor weight and volume in an A549 mouse xenograft model at 10 mg/kg; reduces colonic inflammatory cell infiltration and colonic shortening in a mouse model of DSS-induced ulcerative colitis at 5 mg/kg; improves LPS-induced memory impairments and decreases hippocampal and frontal cortex levels of TNF-α, IL-1β, and IL-6 in LPS-challenged mice
Cayman Chemical RomIfIdInhydrochlorIde 50mg
An α2-AR agonist; epidural administration induces antinociception and sedation in donkeys at 50 UG/kg; induces bradycardia in horses from 0.04-0.12 mg/kg
Cayman Chemical HomobrasInolIde 50mg
A brassinosteroid; field application increases the number of fruits per plant, fruit length, and fruit breadth in tomato plants at 0.12 g/ha
Cayman Chemical 3amInoLTyrosInhydrochlo 100mg
A tyrosine derivative; completely inhibits the growth of a tyrosine-sensitive mutant of N. crassa at 400 µM; cytotoxic to KG-1 leukemia cells at 200-400 UG/ml; dietary administration decreases fecundity and hatchability of eggs of B. oleae at 0.01 g/100 ml, as well as survival of adult B. oleae at 6 g/100 ml
Cayman Chemical Estron 3sulfATsodIum sal 50mg
A steroid; selectively inhibits OATP1B1 over OATP1B3 (IC50s = 0.06 and 19.3 µM, respectively)
Cayman Chemical Pralatrexate 50mg
A DHFR inhibitor (Ki = 13.4 pM) and antifolate; inhibits growth of acute lymphocytic leukemia cells (IC50 = 0.04 μM), MDA-468, SK-BR-3, and ZR-75-1 breast cancer cells (IC50s = 0.11, 0.28, and 0.26 μM, respectively), and SK-LC8 and SK-LC16 NSCLC cells (IC50s = 0.42 and 0.11 μM, respectively); increases median survival in vivo in an H9 T cell lymphoma mouse xenograft model